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Research Highlights

Chemical hijacking of plant hormone signaling ~ A collaboration between organic chemistry and synthetic biology ~

Professor Keiko Torii (ITbM, Nagoya University; HHMI; University of Washington) and her colleagues, Associate Professor Shinya Hagihara, Designated Associate Professor Naoyuki Uchida and Assistant Professor Koji Takahashi, have succeeded in generating a synthetic plant hormone auxin and its receptor. This may lead to precise control of the physiological activities regulated by auxin as well as further understanding of the mechanism of plant growth and development.

The results of this research have been reported in Nature Chemical Biology.

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A synthetic version of auxin and its protein receptor (light blue) nestle together, creating a matched set that behaves just like the natural one. Credit: Keiko Torii /University of Washington/HHMI and Shinya Hagihara/Nagoya University

Journal Information:

This article "Chemical hijacking of auxin signaling with an engineered auxin-TIR1 pair" by Naoyuki Uchida, Koji Takahashi, Rie Iwasaki, Ryotaro Yamada, Masahiko Yoshimura, Takaho A Endo, Seisuke Kimura, Hua Zhang, Mika Nomoto, Yasuomi Tada, Toshinori Kinoshita, Kenichiro Itami, Shinya Hagihara & Keiko U Torii is published online in Nature Chemical Biology

DOI: 10.1038/nchembio.2555

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From the left: Assoc. Prof. Naoyuki Uchida, Prof. Keiko Torii, Assoc. Prof. Shinya Hagihara, Assis. Prof. Koji Takahashi

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2018-01-23

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