Tsuyoshi Hirota

Profile

1998 B.S.; The University of Tokyo (Biochemistry and Molecular Biology)

2000 M.S.; The University of Tokyo (Biochemistry and Molecular Biology)

1998-2000 Visiting Scholar; National Institute for Physiological Sciences, Japan

2000-2003 JSPS Fellow (DC1)

2003 Ph.D.; The University of Tokyo (Biochemistry and Molecular Biology)

2003-2007 Project Assistant Professor; The University of Tokyo

2007 Research Associate; The Scripps Research Institute, La Jolla, USA

2007-2008 Postdoctoral Scholar; University of California San Diego, La Jolla, USA

2008-2010 Visiting Scientist; Genomics Institute of the Novartis Research Foundation, San Diego, USA

2008-2012 Assistant Research Specialist; University of California San Diego, La Jolla, USA

2012-2013 Associate Research Specialist; University of California San Diego, La Jolla, USA

2013-2014 Research Associate; University of Southern California, Los Angeles, USA

2014-present Co-Principal Investigator; Designated Associate Professor; WPI-ITbM, Nagoya University

2014-present PRESTO Researcher (concurrent)

Tsuyoshi Hirota (Co-Principal Investigator, Designated Associate Professor, Nagoya University)
Website thirota::itbm.nagoya-u.ac.jp

Circadian Rhythms, Chemical Biology, Biochemistry and Molecular Biology

By using the resources of clock modifying compounds and genes in combination with state-of-the-art technologies at ITbM, the Kay-Hirota group aims to discover "transformative bio-molecules" that will revolutionize clock research and ultimately benefit human health. A unique combination of molecular, genetic, genomic, biochemical, and chemical biology approaches will allow us to reveal key regulatory processes of the circadian clock and define molecular links between the clock and rhythmic regulation of physiology and behavior. Proof-of-concept chemical probes will provide useful tools to control clock function in a conditional manner and also act as starting points for developing therapeutics for circadian clock-related disorders.

Research Highlights

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