Research Highlights
Efficient synthesis of triarylmethanes - sequential incorporation of aryl rings by palladium catalysts -
Efficient synthesis of triarylmethanes - sequential incorporation of aryl rings by palladium catalysts -
Abstract:
Unsymmetric triarylmethanes have been synthesized starting from methyl phenyl sulfone as an inexpensive and readily available template. The three aryl groups were installed through two sequential palladium-catalyzed C-H arylation reactions, followed by an arylative desulfonation.
Journal Information:
"Modular Synthesis of Triarylmethanes through Palladium-Catalyzed Sequential Arylation of Methyl Phenyl Sulfone " Masakazu Nambo, Cathleen M. Crudden, Angew. Chem. Int. Ed. 53, 742-746 (2013)
Links:
2013-12-05