Research Highlights

Selective Functionalization Synthesizes Chemotherapeutic Natural Products

Abstract:

Through an extensive international collaboration, Professor Huw Davies and Katie Chepiga of Emory University, along with Professor Kenichiro Itami, Junichiro Yamaguchi and Atsushi Yamaguchi at the Institute of Transformative Bio-Molecules (ITbM) of Nagoya University have synthesized marine alkaloids with anti-cancer and therapeutic properties through a sequential C-H functionalization strategy.

Journal Information:

"Concise Syntheses of Dictyodendrins A and F by a Sequential C-H Functionalization Strategy" Atsushi D. Yamaguchi, Kathryn M. Chepiga, Junichiro Yamaguchi, Kenichiro Itami, and Huw M. L. Davies, Journal of the American Chemical Society (2015)

DOI:10.1021/ja512059d

Links:

• Press Release

• Center for Selective C-H Functionalization

Professor Kenichiro Itami: http://www.itbm.nagoya-u.ac.jp/en_backup/members/k-itami/

　　　　　　　　　　Prof. Itami　　　　　Associate Prof. Yamaguchi　　　 Prof. Davies

　　　　　　　

Media Coverage and Related Links:

• ResearchSEA "Selective Functionalization Synthesizes Chemotherapeutic Natural Products" (Jan 7, 2015)
• EurekAlert! "Selective Functionalization Synthesizes Chemotherapeutic Natural Products" (Jan 7, 2015)
• Phys.Org "Selective Functionalization Synthesizes Chemotherapeutic Natural Products" (Jan 7, 2015)
• Science Daily "Selective Functionalization Synthesizes Chemotherapeutic Natural Products" (Jan 7, 2015)
• Science Newsline "Selective Functionalization Synthesizes Chemotherapeutic Natural Products" (Jan 7, 2015)
• Breaking News "Selective Functionalization Synthesizes Chemotherapeutic Natural Products" (Jan 7, 2015)
• Health Medicine Network "Selective Functionalization Synthesizes Chemotherapeutic Natural Products" (Jan 7, 2015)
• Bright Surf "Selective Functionalization Synthesizes Chemotherapeutic Natural Products" (Jan 7, 2015)
• Sci Casts "Selective Functionalization Synthesizes Chemotherapeutic Natural Products" (Jan 8, 2015)
• Medical News Today "Chemotherapeutic natural products synthesized through selective functionalization " (Jan 10, 2015)
• eScience Commons "Global bonds boost chemists' pace of research and discovery" (Jan 15, 2015)
• Emory news center "Global bonds boost chemists' pace of research and discovery" (Jan 16, 2015)

2015-01-07

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