Research Highlights
Chemical hijacking of plant hormone signaling ~ A collaboration between organic chemistry and synthetic biology ~
Professor Keiko Torii (ITbM, Nagoya University; HHMI; University of Washington) and her colleagues, Associate Professor Shinya Hagihara, Designated Associate Professor Naoyuki Uchida and Assistant Professor Koji Takahashi, have succeeded in generating a synthetic plant hormone auxin and its receptor. This may lead to precise control of the physiological activities regulated by auxin as well as further understanding of the mechanism of plant growth and development.
The results of this research have been reported in Nature Chemical Biology.
A synthetic version of auxin and its protein receptor (light blue) nestle together, creating a matched set that behaves just like the natural one. Credit: Keiko Torii /University of Washington/HHMI and Shinya Hagihara/Nagoya University
Journal Information:
This article "Chemical hijacking of auxin signaling with an engineered auxin-TIR1 pair" by Naoyuki Uchida, Koji Takahashi, Rie Iwasaki, Ryotaro Yamada, Masahiko Yoshimura, Takaho A Endo, Seisuke Kimura, Hua Zhang, Mika Nomoto, Yasuomi Tada, Toshinori Kinoshita, Kenichiro Itami, Shinya Hagihara & Keiko U Torii is published online in Nature Chemical Biology
Public access to manuscript (PubMed Central)
From the left: Assoc. Prof. Naoyuki Uchida, Prof. Keiko Torii, Assoc. Prof. Shinya Hagihara, Assis. Prof. Koji Takahashi
Media Coverage and Related Links
- Howard Hughes Medical Institute "Lab-made Hormone May Reveal Secret Lives of Plants" (January 22, 2018)
- University of Washington "Lab-made Hormone May Reveal Secret Lives of Plants" (January 22, 2018)
- EurekAlert! "Lab-made Hormone May Reveal Secret Lives of Plants" (January 22, 2018)
- Phys.Org "Lab-made Hormone May Reveal Secret Lives of Plants" (January 22, 2018)
- Science Newsline "Lab-made Hormone May Reveal Secret Lives of Plants" (January 22, 2018)
- My Science "Lab-made Hormone May Reveal Secret Lives of Plants" (January 22, 2018)
- Newswise "Lab-made Hormone May Reveal Secret Lives of Plants" (January 22, 2018)
- Yonhapnews "Success in making plant hormone and receptor for plant development" in Korean (January 22, 2018)
- Lab Manager "Lab-made Hormone May Reveal Secret Lives of Plants" (January 23, 2018)
- Technology Networks "Lab-made Hormone May Reveal Secret Lives of Plants" (January 24, 2018)
- GARNet Community Blog "Bumping into a hole understanding of auxin signaling" (January 29, 2018)
- IFT "Lab-engineered plant hormone could help regulate fruit growth" (February 20, 2018)
2018-01-23