The research in the Frommer group at ITbM works in four areas: (i) Engineering of genetically encoded biosensors and sponges for in vivo biochemistry, (ii) Characterization of the determinants of interactions between small molecules and transporters to help identifying novel drugs and agrochemicals; (iii) The search for yet unidentified receptors for small molecules; and (iv) Chemical genomics and imaging of processes related to cellular growth and dynamics.