Research Highlights
"Pick 'n' Mix" chemistry to grow cultures of bioactive molecules
Abstract:
Professor Jeffrey Bode and colleagues at ETH-Zürich and ITbM, Nagoya University have developed a new method to build large libraries of bioactive molecules - which can be used directly for biological assays - by simply mixing a small number of building blocks in water.
Journal Information:
"Synthetic fermentation of bioactive non-ribosomal peptides without organisms, enzymes or reagents" Yi-Lin Huang and Jeffrey W. Bode, Nature Chemistry, 2014, Advanced Online Publication
Links:
- Press Release
- Chemistry World "Bringing chemical synthesis to the masses" (September 7, 2014)
- ResearchSEA ""Growing" molecules on plates " (September 8, 2014)
- EurekAlert! "'Pick 'n' Mix' chemistry to grow cultures of bioactive molecules" (September 8, 2014)
- Genetic Engineering and Biotechnology News ""Synthetic Fermentation" Fills Gap between Molecular Synthesis and Microbial Fermentation" (September 8, 2014)
- Science Codex "'Pick 'n' Mix' chemistry to grow cultures of bioactive molecules" (September 8, 2014)
- Phys.Org "'Pick 'n' Mix' chemistry to grow cultures of bioactive molecules" (September 8, 2014)
- Science Newsline "'Pick 'N' Mix' Chemistry to Grow Cultures of Bioactive Molecules" (September 8, 2014)
- Press-News.Org "'Pick 'n' Mix' chemistry to grow cultures of bioactive molecules" (September 8, 2014)
- nanowerk "'Pick 'N' Mix' Chemistry to Grow Cultures of Bioactive Molecules" (September 8, 2014)
- Science Daily "'Pick 'N' Mix' Chemistry to Grow Cultures of Bioactive Molecules" (September 8, 2014)
- 'Pick 'n' Mix' chemistry to grow cultures of bioactive molecules featured in Chemistry News, Internet Medicine, technobahn, Chemistry 2011 (September 8, 2014), Chemistry Times (September 24, 2014)
- Chemical & Engineering News "Building Block Chemistry Makes Complex Unnatural Peptides Simply" (September 8, 2014, Access to members only)
- Innovations Report ""Growing" molecules on plates" (September 10, 2014)
- Revo Science ""Growing" molecules on plates" (September 10, 2014)
- Nature Chemistry "Public Libraries" (September 22, 2014)
- Nature Chemistry Editorial "Inspiration comes naturally" (September 22, 2014)
- tekno scienze "'Pick 'n' Mix' chemistry to grow cultures of bioactive molecules" (October 24, 2014)
- ResearchSEA "Future antibiotic-making kits for amateurs?* " (April 2, 2015)
- Nanowerk "Future antibiotic-making kits for amateurs?* " (April 2, 2015)
- Machines Like Us "Future antibiotic-making kits for amateurs?* " (April 2, 2015)
- Science Daily "Future antibiotic-making kit for amateurs? Kit could one day be widely available" (April 2, 2015)
- Asia Research News 2015 "Future antibiotic-making kits for amateurs?* " (April 2, 2015)
Professor Jeffrey Bode: http://www.itbm.nagoya-u.ac.jp/en_backup/members/j-bode/
Media Coverage and Related Links:
2014-09-08