Nagoya University

Graduate Program of Transformative Chem-Bio Research

EVENTS

GTR ORGANIC SEMINARS

Date:July 17(Wed),2024,16:30-18:00
Venue:Fuji hall, EI Bldg.2F
Speaker:Dr. Xin-Yuan Liu (Professor, Department of Chemistry, SUSTech, China)
Title:Cu/Chiral Anionic Ligand-Catalyzed Enantioselective Radical Reactions

Representative Publications
1. "Enantioconvergent Cu-catalysed N-alkylation of aliphatic amines", Ji-Jun Chen, Jia-Heng Fang, Xuan-Yi Du, Jia-Yong Zhang, Jun-Qian Bian, Fu-Li Wang, Cheng Luan, Wei-Long Liu, Ji-Ren Liu, Xiao-Yang Dong, Zhong-Liang Li, Qiang-Shuai Gu, Zhe Dong, and Xin-Yuan Liu*. Nature 2023, 618, 294.
2. "A general copper-catalysed enantioconvergent C(sp3)-S cross-coupling via biomimetic radical homolytic substitution", Yu Tian, Xi-Tao Li , Ji-Ren Liu, Jian Cheng, Ang Gao, Ning-Yuan Yang, Zhuang Li, Kai-Xin Guo, Wei Zhang, Han-Tao Wen, Zhong-Liang Li, Qiang-Shuai Gu, Xin Hong & Xin-Yuan Liu*. Nat. Chem. 2023, DOI: 10.1038/s41557-023-01385-w.
3. "Cu-catalysed enantioselective radical heteroatomic S-O cross-coupling", Yong-Feng Cheng, Zhang-Long Yu, Yu Tian, Ji-Ren Liu, Han-Tao Wen, Na-Chuan Jiang, Jun-Qian Bian, Guo-Xiong Xu, Dan-Tong Xu, Zhong-Liang Li, Qiang-Shuai Gu ,* Xin Hong * and Xin-Yuan Liu *. Nat. Chem. 2023, 15, 395.
4. "Mechanism-Based Ligand Design for Copper-Catalysed Enantioconvergent C(sp3)-C(sp) Cross-Coupling of Tertiary Electrophiles with Alkynes", Fu-Li Wang; Chang-Jiang Yang; Ji-Ren Liu; Ning-Yuan Yang; Xiao-Yang Dong; Ruo-Qi Jiang; Xiao-Yong Chang ; Zhong-Liang Li; Guo-Xiong Xu; Dai-Lei Yuan; Yu-Shuai Zhang; Qiang-Shuai Gu;* Xin Hong ;* Xin-Yuan Liu* . Nat. Chem. 2022, 14, 949-957.
5. "A General Asymmetric Copper-Catalysed Sonogashira C(sp3)-C(sp) Coupling", Xiao-Yang Dong; Yu-Feng Zhang; Can-Liang Ma; Qiang-Shuai Gu; Fu-Li Wang; Zhong-Liang Li; Sheng-Peng Jiang; Xin-Yuan Liu*. Nat. Chem. 2019, 11, 1158-1166.
6. "Cu-Catalysed Intramolecular Radical Enantioconvergent Tertiary β-C(sp3)-H Amination of Racemic Ketones", Chang-Jiang Yang; Chi Zhang; Qiang-Shuai Gu; Jia-Heng Fang; Xiao-Long Su; Liu Ye; Yan Sun; Yu Tian; Zhong-Liang Li; Xin-Yuan Liu*. Nat. Catal. 2020, 3, 539-546.
7. "Catalytic Enantioselective Desymmetrizing Functionalization of Alkyl Radicals via Cu(I)/CPA Cooperative Catalysis", Yong-Feng Cheng; Ji-Ren Liu; Qiang-Shuai Gu; Zhang-Long Yu; Jian Wang; Zhong-Liang Li; Jun-Qian Bian; Han-Tao Wen; Xiao-Jing Wang; Xin Hong;* Xin-Yuan Liu*. Nat. Catal. 2020, 3, 401-410.
8. "Copper(I)-Catalyzed Asymmetric Reactions Involving Radicals", Qiang-Shuai Gu; Zhong-Liang Li; Xin-Yuan Liu*. Acc. Chem. Res. 2020, 53, 170-181.
9. "A general copper-catalysed enantioconvergent radical Michaelis-Becker-type C(sp3)-P cross-coupling", Li-Lei Wang, Huan Zhou, Yu-Xi Cao, Chi Zhang, Yang-Qing Ren, Zhong-Liang Li, Qiang-Shuai Gu, Xin-Yuan Liu*. Nat. Synth. 2023, 2, 430.
10. "Recent Advances in Copper-Catalysed Radical-Involved Asymmetric 1,2
-Difunctionalization of Alkenes", Zhong-Liang Li; Gui-Chun Fang; Qiang-Shuai Gu; Xin-Yuan Liu*. Chem. Soc. Rev. 2020, 49, 32-48.

Language:English
Host:Kazuaki Ishihara ishihara<at>cc.nagoya-u.ac.jp (<at>→@)

★GTR international students only
These seminars are "GTR Lecture series on multidisciplinary problems (1pt/each)".
Enroll in gtr e-portfolio (Dead line: July 15 ).Grades will be judged by report. Report submission from TACT by July 31st.