Takashi Ooi
Principal Investigator, Professor
Website:http://www.chembio.nagoya-u.ac.jp/labhp/organic3/index_e.html
E-mail:tooi[at]apchem.nagoya-u.ac.jp (Please replace [at] with @ when sending an email.)
Organic ion pair catalysis, molecular recognition, molecule activation, pharmaceuticals
Ooi has been creating a bold stream of research on the molecular design of various chiral organic ion pairs and their rational structural modifications for eliciting unique functions as molecular catalysts, providing a solid basis for safe and sustainable supply of useful organic compounds. His accomplishments have had a significant impact on the frontiers of chemistry in terms of developing a fundamental understanding of the relationship between the three-dimensional structure of a chiral organic ion pair and its catalytic and stereocontrolling abilities. He will be involved mainly in the development of molecules that selectively induce plant growth, molecules that improve animal reproduction, and molecules that can overcome species barrier, collaborating with the groups of Kinoshita, Yoshimura, Higashiyama, Bode, and Itami.
Profile
1989 | B.S.; Nagoya University (Applied Chemistry & Synthetic Chemistry) |
1991 | M.S.; Nagoya University (Applied Chemistry) |
1994 | Dr. Eng.; Nagoya University (Applied Chemistry) |
1992-1994 | JSPS Research Fellow (DC) |
1994-1995 | JSPS Research Fellow; Massachusetts Institute of Technology, USA |
1995-1998 | Assistant Professor; Faculty of Science, Hokkaido University |
1998-2000 | Lecturer; Faculty of Science, Hokkaido University |
2001-2006 | Associate Professor; Graduate School of Science, Kyoto University |
2006-present | Professor; Graduate School of Engineering, Nagoya University |
2013-present | Professor; WPI-ITbM, Nagoya University |
2013-present | Research Representative; JST CREST Project |
Selected Awards and Honors
2014 | Fellow of the Royal Society of Chemistry (FRSC) |
2013 | Inoue Prize for Science, Inoue Foundation |
2011 | IBM Japan Science Prize |
2010 | JSPS Prize, Japan Society for the Promotion of Sciences |
2008 | ACP Lectureship Award, Taiwan |
Selected Publications
- Ohmatsu, K.; Imagawa, N.; Ooi, T. Nature Chem. 2014, 6, 47-51. Ligand-enabled Multiple Absolute Stereocontrol in Metal-catalysed Cycloaddition for Construction of Contiguous All-carbon Quaternary Stereocentres. DOI: 10.1038/nchem.1796
- Ohmatsu, K.; Ando, Y.; Ooi, T. J. Am. Chem. Soc. 2013, 135, 18706-18709. Asymmetric Substitution at the Tetrasubstituted Chiral Carbon: Catalytic Ring-Opening Alkylation of Racemic 2,2-Disubstituted Aziridines with 3-Substituted Oxindoles. DOI: 10.1021/ja411647x
- Uraguchi, D.; Tsutsumi, R.; Ooi, T. J. Am. Chem. Soc. 2013, 135, 8161-8164. Catalytic Asymmetric Oxidation of N-Sulfonyl Imines with Hydrogen Peroxide-Trichloroacetonitrile System. DOI: 10.1021/ja403491j
- Ohmatsu, K.; Ito, M.; Kunieda, T.; Ooi, T. Nature Chem. 2012, 4, 473-477. Ion-paired Chiral Ligands for Asymmetric Palladium Catalysis. DOI: 10.1038/nchem.1311
- Uraguchi, D.; Ueki, Y.; Ooi, T. Science 2009, 326, 120-123. Chiral Organic Ion Pair Catalysts Assembled Through a Hydrogen-Bonding Network. DOI: 10.1126/science.1176758
- Members
- Yoshimura Group
- Yamaguchi Group
- Bode Group
- Crudden Group
- Frommer Group
- Itami Group
- Kamikouchi Group
- Hirota Group (collaborating with Kay)
- Kinoshita Group
- Ooi Group
- Tama Group
- Shimotohno Group (collaborating with Torii)
- Tsuchiya Group
- Yanai Group
- Laohavisit Group
- Mizuta Group
- Phung Group
- Kurihara Group
- Molecular Structure Center
- Live Imaging Center
- Chemical Library Center
- Peptide Protein Center
- Administrative Department
- Affiliated Researchers