Masakazu Nambo
Co-Principal Investigator, Designated Associate Professor
Website:https://nagoya-uni-cruddengroup-en.labby.jp/
E-mail:mnambo[at]itbm.nagoya-u.ac.jp (Please replace [at] with @ when sending an email.)
Organic synthesis, Transition metal catalysis, Nanocarbon chemistry
Multiply arylated methanes including triarylmethanes are valuable structures in functional materials and biologically active compounds. Thus, it is becoming increasingly important to develop efficient and modular route to these species. Friedel-Crafts arylations and reductive dehydroxylations of arylmethanol derivatives are typically employed to access triarylmethanes. Recently, transition-metal catalyzed cross coupling reactions have also been developed. However, these methods often suffer from the formation of undesired regioisomers and the need to prepare reactive intermediates / coupling partners leading to lengthy multi-step syntheses.
Our group has recently established a modular synthesis of triarylmethanes and triarylacetonitriles through a Pd-catalyzed sequential arylation strategy. These methods does not only provide a new synthetic approach to multiply arylated methanes starting from readily available haloarenes and arylboronic acids, but is also applicable to the preparation of unexplored materials and pharmaceuticals.
Profile
2006 | B.S.; Nagoya University (Chemistry; Supervisors: Univ. Prof. Ryoji Noyori, Prof. Susumu Saito) |
2008 | M.S.; Nagoya University (Chemistry; Supervisors: Prof. Ryoji Noyori, Prof. Kenichiro Itami) |
2011 | Ph.D.; Nagoya University (Chemistry; Supervisor: Prof. Kenichiro Itami) |
2008-2011 | JSPS Research Fellow (DC1) |
2008 | Exchange Student; (Münster University, Germany, Supervisor: Prof. Bernhard Wünsch) |
2011-2013 | Research Scientist; Asahi-Kasei Corporation, Japan |
2013-present | Co-Principal Investigator, Designated Assistant Professor; WPI-ITbM, Nagoya University |
2018-2021 | Co-Principal Investigator, Designated Lecturer; WPI-ITbM, Nagoya University |
2021-present | Co-Principal Investigator, Designated Associate Professor; WPI-ITbM, Nagoya University |
Selected Awards and Honors
2017 | SYNLETT Best Paper Award 2017 |
2016 | CSJ Presentation Award, The 97th CSJ Annual Meeting |
- Members
- Yoshimura Group
- Yamaguchi Group
- Bode Group
- Crudden Group
- Frommer Group
- Itami Group
- Kamikouchi Group
- Hirota Group (collaborating with Kay)
- Kinoshita Group
- Ooi Group
- Tama Group
- Shimotohno Group (collaborating with Torii)
- Tsuchiya Group
- Yanai Group
- Laohavisit Group
- Mizuta Group
- Phung Group
- Kurihara Group
- Molecular Structure Center
- Live Imaging Center
- Chemical Library Center
- Peptide Protein Center
- Administrative Department
- Affiliated Researchers