Shigehiro Yamaguchi
Vice-Director of ITbM, Principal Investigator, Professor
Website:http://orgreact.chem.nagoya-u.ac.jp/en/index.html
E-mail:yamaguchi[at]chem.nagoya-u.ac.jp (Please replace [at] with @ when sending an email.)
Fluorescent molecules, molecular design, physical organic chemistry
Yamaguchi works on a variety of topics in the general fields of main group chemistry and physical organic chemistry. In particular, emphasis is placed on the development of new functional π-electron materials possessing unusual photophysical and electronic properties. On the basis of the new design concepts emanating from his lab, he is able to exploit the features of various main group elements as well as the newly developed synthetic methodologies, various types of functional materials have been developed; including the key molecule in commercial organic electroluminescent devises. He will be involved mainly in the development of innovative bio-imaging tools, collaborating with the groups of Higashiyama, Irle, Itami, and Crudden.
Profile
1991 | B.S.; Kyoto University (Synthetic Chemistry) |
1993 | M.S.; Kyoto University (Synthetic Chemistry and Biological Chemistry) |
1997 | Dr. Eng.; Kyoto University (Synthetic Chemistry and Biological Chemistry) |
1993 | JSPS Research Fellow (DC) |
1993-2002 | Assistant Professor; Institute for Chemical Research, Kyoto University |
2001-2004 | JST PRESTO Researcher |
2003-2005 | Associate Professor; Graduate School of Science, Nagoya University |
2004-2007 | Research Representative; JST SORST Project |
2005-2012 | Professor; Graduate School of Science, Nagoya University |
2010-2016 | Research Representative; JST CREST Project |
2012-present | Professor; Research Center for Materials Science, Nagoya University |
2013-present | Professor; WPI-ITbM, Nagoya University |
2014-present | Vice-Director; WPI-ITbM, Nagoya University |
2017-present | Director; Research Center for Materials Science, Nagoya University |
Research Highlights
- A fluorescent dye that survives in live cell STED imaging ~A new molecular tool for continuous super-resolution fluorescence microscopy~
- Super-photostable fluorescent labeling agent for super-resolution microscopy ~ A powerful tool for 3D and multicolor STED imaging of cellular ultrastructure ~
- Taking a deep look: a near infrared fluorescent dye for long term bioimaging ~ Promising photostable tool for single molecule tracking and multicolor imaging ~
Selected Awards and Honors
2015 | 33rd Academic Award, Chemical Society of Japan |
2015 | Mukaiyama Award |
2012 | JSPS Prize, Japan Society for the Promotion of Sciences |
2009 | DIC Award from Synthetic Organic Chemistry, Japan |
2008 | Nozoe Award for Young Scientists |
2008 | NISTEP Nice Step Researcher |
2007 | Tokyo Techno Forum 21 Gold Medal |
Selected Publications
- Fukazawa, A.; Karasawa, T.; Zhang, H.; Minemura, K.; Camacho, C.; Wang, J.; Irle, S.; Yamaguchi, S. Angew. Chem. Int. Ed. 2013, 52, 10519-10523. Photochemical Double 5-exo-dig Cyclization of Alkenyl-substituted Dithienylacetylenes: Efficient Synthesis of Diarylated Dithienofulvalenes. DOI: 10.1002/anie.201303738
- Kushida, T.; Yamaguchi, S.; Angew. Chem. Int. Ed. 2013, 52, 8054-8058. Boracyclophanes: Modulation of the σ/π Character in Boron-Benzene Interactions. DOI: 10.1002/anie.201303830
- Yuan, C.; Saito, S.; Camacho, C.; Irle, S.; Hisaki, I.; Yamaguchi, S. J. Am. Chem. Soc., 2013, 135, 8842-8845. A π-Conjugated System with Flexibility and Rigidity that Shows Environment-Dependent RGB Luminescence DOI: 10.1021/ja404198h
- Iida, A.; Saito, S.; Sasamori, T.; Yamaguchi, S. Angew. Chem. Int. Ed. 2013, 52, 3760-3764. Borylated Dibenzoborepin Synthesized via Skeletal Rearrangement and its Photochromism Based on Bora-Nazarov Cyclization. DOI: 10.1002/anie.201210236
- Fukazawa, A.; Oshima, H.; Shiota, Y.; Takahashi, S.; Yoshizawa, K.; Yamaguchi, S. J. Am. Chem. Soc., 2013, 135, 1731-1734. Thiophene-Fused Bisdehydro[12]annulene that Undergoes Transannular Alkyne Cycloaddition Either by Light or Heat. DOI: 10.1021/ja3126849
- Members
- Yoshimura Group
- Yamaguchi Group
- Bode Group
- Crudden Group
- Frommer Group
- Itami Group
- Kamikouchi Group
- Hirota Group (collaborating with Kay)
- Kinoshita Group
- Ooi Group
- Tama Group
- Shimotohno Group (collaborating with Torii)
- Tsuchiya Group
- Yanai Group
- Laohavisit Group
- Mizuta Group
- Phung Group
- Kurihara Group
- Molecular Structure Center
- Live Imaging Center
- Chemical Library Center
- Peptide Protein Center
- Administrative Department
- Affiliated Researchers