Tsuyoshi Hirota

Co-Principal Investigator, Designated Associate Professor

Website：http://www.itbm.nagoya-u.ac.jp/en/kay-hirota_group/
E-mail：thirota[at]itbm.nagoya-u.ac.jp　(Please replace [at] with @ when sending an email.)

Circadian Rhythms, Chemical Biology, Biochemistry and Molecular Biology
By using the resources of clock modifying compounds and genes in combination with state-of-the-art technologies at ITbM, the Kay-Hirota group aims to discover "transformative bio-molecules" that will revolutionize clock research and ultimately benefit human health. A unique combination of molecular, genetic, genomic, biochemical, and chemical biology approaches will allow us to reveal key regulatory processes of the circadian clock and define molecular links between the clock and rhythmic regulation of physiology and behavior. Proof-of-concept chemical probes will provide useful tools to control clock function in a conditional manner and also act as starting points for developing therapeutics for circadian clock-related disorders.

Profile

1998B.S.; The University of Tokyo (Biochemistry and Molecular Biology)
2000M.S.; The University of Tokyo (Biochemistry and Molecular Biology)
1998-2000Visiting Scholar; National Institute for Physiological Sciences, Japan
2000-2003JSPS Fellow (DC1)
2003Ph.D.; The University of Tokyo (Biochemistry and Molecular Biology)
2003-2007Project Assistant Professor; The University of Tokyo
2007Research Associate; The Scripps Research Institute, La Jolla, USA
2007-2008Postdoctoral Scholar; University of California San Diego, La Jolla, USA
2008-2010Visiting Scientist; Genomics Institute of the Novartis Research Foundation, San Diego, USA
2008-2012Assistant Research Specialist; University of California San Diego, La Jolla, USA
2012-2013Associate Research Specialist; University of California San Diego, La Jolla, USA
2013-2014Research Associate; University of Southern California, Los Angeles, USA
2014-presentCo-Principal Investigator; Designated Associate Professor; WPI-ITbM, Nagoya University
2014-presentPRESTO Researcher (concurrent)

Research Highlights