RESEARCHERID

Toshinori Kinoshita

Principal Investigator, Professor

Website：http://plantphys.bio.nagoya-u.ac.jp/en/index.html
E-mail：kinoshita[at]bio.nagoya-u.ac.jp　(Please replace [at] with @ when sending an email.)

Plant molecular biology, plant chemical biology, stomata, auxin, plant growth
Kinoshita has been studying signaling pathways of stomatal opening and closing, and molecular mechanisms of plant cell growth in response to the phytohormone auxin. By using genetic, biochemical, and physiological approaches, he has identified the key components regulating stomatal opening and closing reported by Darwin in 1898. More recently, he reported evidence for the existence of an unidentified auxin receptor responsible for plant growth, which became the basis of one of the core projects in this Institute. He will be involved mainly in the development of molecules that selectively induce plant growth, collaborating with the groups of Itami, Crudden, Ooi, and Torii.

Profile

1991B.S.; Kyushu University (Biological Science)
1993M.S.; Kyushu University (Biological Science)
1994Dr. Sci.; Kyushu University (Biological Science)
1993-1994JSPS Research Fellow (DC1)
1994-1999Research Associate; School of Sciences, Kyushu University
1999-2007Assistant Professor; Faculty of Sciences, Kyushu University
2005-2009JST PRESTO Researcher
2007-2010Associate Professor; Graduate School of Science, Nagoya University
2010-presentProfessor; Graduate School of Science, Nagoya University
2013-2023Director; Gene Research Center, Nagoya University
2013-presentProfessor; WPI-ITbM, Nagoya University

Research Highlights

Selected Awards and Honors

2024

Highly Cited Researchers 2024
2024

6th Photobiology Association of Japan Award
2023

Highly Cited Researchers 2023
2015-2019 Project Leader for Scientific Research on Innovative Areas, MEXT Grant-in-Aid Project
2015 The Botanical Society of Japan, Journal of Plant Research, Best Paper Award
2007 Minister Award for Distinguished Young Scientists

Selected Publications

  • Hayashi Y, Fukatsu K, Takahashi K, Kinoshita SN, Kato K, Sakakibara T, Kuwata K, Kinoshita T. Nature Communications, 2024, 15:1194. Phosphorylation of plasma membrane H+-ATPase Thr881 participates in light-induced stomatal opening. DOI: 10.1038/s41467-024-45248-5
  • Aihara Y, Maeda B, Goto K, Takahashi K, Toh S, Ye W, Toda Y, Uchida M, Asai E, Sato A, Itami K, Murakami K, Kinoshita T. Nature Communications, 2023, 14: 2665. Identification and improvement of isothiocyanate-based inhibitors on stomatal opening to act as drought tolerance-conferring agrochemicals. DOI: 10.1038/s41467-023-38102-7
  • Zhang M, Wang Y, Chen X, Xu F, Ding M, Ye W, Kawai Y, Toda Y, Hayashi Y, Suzuki T, Zeng H, Xiao L, Xiao X, Xu J, Guo S, Yan F, Shen Q, Xu G, Kinoshita T, Zhu Y. Nature Communications, 2021, 12, 735. Plasma membrane H+-ATPase overexpression increases rice yield via simultaneous enhancement of nutrient uptake and photosynthesis. Nature Communications 12, 735. DOI: 10.1038/s41467-021-20964-4
  • Wang, Y.; Noguchi, K.; Ono, N.; Inoue, S.; Terashima, I.; Kinoshita, T. Proc. Natl. Acad. Sci. USA. 2014, 111, 533. Overexpression of plasma membrane H+-ATPase in guard cells promotes light-induced stomatal opening and enhances plant growth. DOI: 10.1073/pnas.1305438111
  • Takahashi, K.; Hayashi, K.; Kinoshita, T. Plant Physiol. 2012, 159, 632. Auxin activates the plasma membrane H+-ATPase by phosphorylation during hypocotyl elongation in Arabidopsis thaliana. DOI: 10.1104/pp.112.196428
  • Kinoshita, T.; Ono, N.; Hayashi, Y.; Morimoto, S.; Nakamura, S.; Soda, M.; Kato, Y.; Ohnishi, M.; Nakano, T.; Inoue, S.; Shimazaki, K. Curr. Biol. 2011, 21, 1232. FLOWERING LOCUS T regulates stomatal opening. DOI: 10.1016/j.cub.2011.06.025
  • Kinoshita, T.; Cano-Delgado, A.; Seto, H.; Hiranuma, S.; Fujioka, S.; Yoshida, S.; Chory, J. Nature 2005, 433, 167. Binding of brassinosteroids to the extracellular domain of plant receptor kinase BRI1. DOI: 10.1038/nature03227
  • Kinoshita, T.; Doi, M.; Suetsugu, N.; Kagawa, T.; Wada, M.; Shimazaki, K. Nature 2001, 414, 656. phot1 and phot2 mediate blue light regulation of stomatal opening. DOI: 10.1038/414656a